Therefore, MODURETIC should be avoided, if possible, in diabetic patients and, if it is used, serum electrolytes and renal function must be monitored frequently. Symptoms of serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing. The risk of hyperkalemia may be increased when potassium-conserving agents, including MODURETIC, are administered concomitantly with an angiotensin-converting enzyme inhibitor, an angiotensin II receptor antagonist, cyclosporine or tacrolimus. USES: Amiloride is used with hydrochlorothiazide to treat donde puedo comprar amiloride sin receta high blood pressure hypertension certain heart problems congestive heart failure or swelling edema that may be caused by severe liver problems. This may rarely cause serious side effects such as muscle weakness or slow irregular heartbeat.